Case Study – From Discovery to Practice and Survivorship

The Georgia Clinical & Translational Science Alliance- Georgia CTSA and Southern California Clinical and Translational Science Institute -SC-CTSI have collaborated to provide free, high quality educational programs for clinical research professionals at novice to expert levels of experience. At the completion of each course or program, participants earn contact hours recognized by a certificate and/or badge.

Description:

The impact of molecular profiling and technologies in translating basic science research to human studies; and the translation of new interventions into clinical practice will be explored.  We will discuss vital programs in the discovery of cancer genome mapping and the advancement of precision health and oncology, including The Cancer Genome Atlas, and the National Cancer Institute Genomic Data Commons.

Topics

1. APOLLO:  Applied Proteogenomics Organizational Learning and Outcomes Network
   • APOLLO-5 Dashboard Pilot
   • From Discovery to Practice and Survivorship: Building a National Real-World Data Learning Healthcare Framework for Military and Veteran Cancer Patient
2. Precision Health and Precision Oncology
3. Phases of Transitional Science
4. Standards and Sharing of Data / New Insights and Understanding
5. Complex Cancer Genome Landscape
6. Cancer Genome Mapping Programs:
   • The Cancer Genome Atlas- Pilot & Expansion Phase
   • The National Cancer Institute Genomic Data Commons
7. Rapid Acceleration from Stimulus Funding (2009-2011)
8. NCI-Match Clinical Trial - NCI-MATCH Central Screening Summary
9. Clinical Proteomic Tumor Analysis Consortium
   • Central Dogma of Biology
   • Re-writing Central Dogma
   • Imaging, genomics and phenomics data
10. Cancer Moonshot Data and Technology Team
11. VA Medical Centers Regional/Corporate Data Warehousing and Analytical Environment (Regions 1-4)
12. MCC Military Clinical Trials Network - MCC Biobank
13. An Integrated TCGA Pan-Cancer Clinical Data Resource to drive High-Quality Survival Outcome Analytics
    • Assessment and Recommended use of the endpoints for OS, PFI, DFI, and DSS
14. Patient Trajectory Comprised of all Relevant Cancer Case and Cofactor Trajectories
15. Treatment landscape for a newly diagnosed metastatic NSCLC patient
16. Translational Data Spheres
17. Patient Trajectory Comprised of all Relevant Cancer Case and Cofactor Trajectories

Speaker:

Jerry S.H. Lee, PhD is an Associate Professor of Clinical Medicine and Chemical Engineering & Material Sciences at the University of Southern California Keck School of Medicine and Viterbi School of Engineering. He also serves as the Chief Science and Innovation Officer for the Lawrence J. Ellison Institute for Transformative Medicine of USC.  Prior to joining USC, Dr. Lee served for more than a decade as a Health Sciences Director within the National Cancer Institute’s Office of the Director. Through direct support and use of public-public/public-private partnerships, he deployed programs focused on the integration of advanced technologies, transdisciplinary approaches, infrastructures, and standards to accelerate the creation of publicly available, broadly accessible, multi-dimensional data, knowledge, and tools to empower the entire cancer research continuum for patient benefit.  In 2016, Dr. Lee was assigned to Office of the Vice President to serve as the Director for Cancer Research and Technology for the White House Cancer Moonshot Task Force. A few key efforts he helped coordinate include: the Applied Proteogenomics Organizational Learning and Outcomes (APOLLO) Network; international collaborations to share molecular characterization datasets;  the Blood Profiling Atlas in Cancer pilot; as well as co-chairing an interagency group focused on cancer data and technology policy issues.  Dr. Lee’s research involves elucidating the interplay between biophysical and biochemical drivers of age-related diseases.  He is a member of the Department of Veterans Affairs’ National Research Advisory Council, the National Academies Board on Science, Technology, and Economic Policy’s Innovation Policy Forum, and the Health and Environmental Sciences Institute’s Board of Trustees. Dr. Lee earned his B.S. degree in biomedical engineering and Ph.D. in chemical and biomolecular engineering from Johns Hopkins University.  jerry@ellison.usc.edu

Audience:

This program is designed for Clinical Research Coordinators, Project Managers, Monitors, Regulatory, Medical and Clinical Affairs Professionals or junior faculty with 3+ years of experience seeking to further develop clinical research conduct skills and principles.  Clinical research professionals should have responsibilities that include clinical trial start up planning, mentoring and complex issues involving site management, study management, and sponsor/ CRO challenges.      

Learner level:  Intermediate/ Advanced

Contact Hours:

Emory Nursing Professional Development Center (ENPDC) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation. Attendees to this CNE activity will be awarded 1.0 Continuing Nursing Education contact hours from ENPDC.

Need Help with Registration? Please contact us at ene@emory.edu or 404-727-9208.

Program Information: This is the fifth course in a five (5)-session program. To complete the entire program and earn a badge CLICK HERE.